Direct flights from Knoxville (TYS)
From Knoxville Mc Ghee Tyson airport, 57 destinations are served non-stop in 1 countries, with about 968 flights a week. With a single stop, 561 more destinations are within reach.
57direct destinations
1countries
≈ 968flights a week
+ 561with 1 stop
AirLabs data, updated 23 Oct 2026. Check schedules and fares with the airlines. “Flights a week”: estimate.
Destinations by continent
North America · 57 destinations
| Destination | Airlines | Distance | Duration | Flights / week | Days |
|---|---|---|---|---|---|
| Charlotte (CLT), United States | OH · OO · PT | 284 km | 1h 24m | ≈ 115 | every day |
| Atlanta (ATL), United States | 9E · DL | 244 km | 1h 06m | ≈ 114 | every day |
| Chicago (ORD), United States | G7 · MQ · OO · UA · YX | 765 km | 2h 02m | ≈ 102 | every day |
| Philadelphia (PHL), United States | G4 · OH · PT | 891 km | 1h 58m | ≈ 59 | every day |
| Dallas (DFW), United States | AA · OH | 1,239 km | 2h 35m | ≈ 56 | every day |
| New York (LGA), United States | 9E · YX | 1,041 km | 2h 06m | ≈ 35 | every day |
| Orlando (SFB), United States | G4 | 823 km | 1h 33m | ≈ 34 | every day |
| Dulles (IAD), United States | C5 · G4 · YV | 675 km | 1h 44m | ≈ 31 | every day |
| Fort Lauderdale (FLL), United States | G4 | 1,143 km | 2h 01m | ≈ 31 | every day |
| Saint Petersburg (PIE), United States | G4 | 886 km | 1h 39m | ≈ 31 | every day |
| Denver (DEN), United States | G4 · UA · WN | 1,867 km | 3h 20m | ≈ 30 | every day |
| Nashville (BNA), United States | LF · WN | 244 km | 1h 05m | ≈ 28 | every day |
| Washington (DCA), United States | 9E · OH | 701 km | 1h 43m | ≈ 28 | every day |
| Detroit (DTW), United States | 9E | 714 km | 1h 44m | ≈ 23 | every day |
| Houston (IAH), United States | OO · YV | 1,241 km | 2h 25m | ≈ 23 | every day |
| Orlando (MCO), United States | G4 · WN | 858 km | 1h 45m | ≈ 22 | every day |
| New York (EWR), United States | G4 · G7 | 1,013 km | 1h 55m | ≈ 20 | every day |
| Fort Walton Beach (VPS), United States | G4 | 637 km | 1h 22m | ≈ 17 | Mon, Wed, Thu, Fri, Sat, Sun |
| Dallas (DAL), United States | JL · WN | 1,225 km | 2h 20m | ≈ 16 | every day |
| Miami (MIA), United States | AA · MQ · YX | 1,168 km | 2h 15m | ≈ 16 | every day |
| Punta Gorda (PGD), United States | G4 | 1,006 km | 1h 53m | ≈ 16 | Mon, Wed, Thu, Fri, Sat, Sun |
| Austin (AUS), United States | AA · DL · G4 · JL · WN | 1,418 km | 2h 35m | ≈ 15 | Mon, Thu, Fri, Sat, Sun |
| Baltimore (BWI), United States | WN | 747 km | 1h 40m | ≈ 14 | every day |
| Minneapolis (MSP), United States | 9E | 1,275 km | 2h 29m | ≈ 13 | every day |
| Las Vegas (LAS), United States | G4 | 2,793 km | 4h 18m | ≈ 11 | Mon, Thu, Fri, Sun |
| Boston (BOS), United States | G4 | 1,334 km | 2h 12m | ≈ 8 | Tue, Wed, Thu, Sat, Sun |
| Phoenix (PHX), United States | G4 | 2,568 km | 4h 01m | ≈ 7 | Mon, Thu, Fri, Sat, Sun |
| Sarasota (SRQ), United States | G4 | 946 km | 1h 42m | ≈ 7 | Thu, Sun |
| Houston (HOU), United States | G4 | 1,257 km | 2h 17m | ≈ 6 | Mon, Fri |
| Jacksonville (JAX), United States | G4 | 629 km | 1h 22m | ≈ 6 | Thu, Sun |
| Memphis (MEM), United States | G4 | 549 km | 1h 19m | ≈ 6 | Fri, Sun |
| Chicago (MDW), United States | G4 | 740 km | 1h 32m | ≈ 5 | Mon, Fri |
| Birmingham (BHM), United States | G7 · OH | 355 km | 0h 49m | ≈ 3 | Fri, Sat, Sun |
| Key West (EYW), United States | G4 | 1,269 km | 2h 04m | ≈ 3 | Mon, Fri |
| Asheville (AVL), United States | DL · G4 | 138 km | 1h 23m | ≈ 2 | Fri |
| New Haven (HVN), United States | XP | 1,139 km | 2h 09m | ≈ 2 | Thu, Sun |
| New York (JFK), United States | 9E | 1,040 km | 1h 57m | ≈ 2 | Wed |
| Bentonville (XNA), United States | 9E | 928 km | 1h 53m | ≈ 1 | Fri |
| Chattanooga (CHA), United States | OO | 139 km | 1h 52m | ≈ 1 | Mon |
| Cincinnati (CVG), United States | 9E | 366 km | 1h 15m | ≈ 1 | Tue |
| Dayton (DAY), United States | OH | 455 km | 0h 57m | ≈ 1 | Thu |
| Greenville (GSP), United States | OH | 190 km | 0h 37m | ≈ 1 | Wed |
| Marion (MWA), United States | PT | 497 km | 1h 37m | ≈ 1 | Thu |
| Middletown (MDT), United States | 9E | 800 km | 2h 00m | ≈ 1 | Mon |
| Montgomery (MGM), United States | 9E | 448 km | 1h 00m | ≈ 1 | Wed |
| Pensacola (PNS), United States | OH | 663 km | 1h 09m | ≈ 1 | Mon |
| Raleigh/Durham (RDU), United States | 9E | 469 km | 1h 00m | ≈ 1 | Wed |
| Tallahassee (TLH), United States | OH | 602 km | 1h 08m | ≈ 1 | Fri |
| Columbia (CAE), United States | JL | 334 km | — | ≈ 0 | — |
| Jackson (MKL), United States | KG | 445 km | — | ≈ 0 | — |
| Lexington (LEX), United States | DL | 254 km | — | ≈ 0 | — |
| New Orleans (MSY), United States | SY | 872 km | — | ≈ 0 | — |
| Niagara Falls (IAG), United States | UJ | 919 km | — | ≈ 0 | — |
| Savannah (SAV), United States | SY | 482 km | — | ≈ 0 | — |
| Shreveport (SHV), United States | LF | 979 km | — | ≈ 0 | — |
| Teterboro (TEB), United States | LF | 1,031 km | — | ≈ 0 | — |
| West Palm Beach (DJT), United States | JL | 1,080 km | — | ≈ 0 | — |
Longest direct flight
Las Vegas (LAS): 2,793 km, about 4h 18m, by Allegiant Air.
Busiest route
Charlotte (CLT): about 115 flights a week (OH, OO, PT).
Single ticket
American Airlines also sells, under its own flight number, flights on 11 routes operated by other airlines (codeshare).
Frequently asked questions
How many direct destinations from Knoxville?
57 destinations in 1 countries, including 57 in North America.
Which airlines fly from Knoxville?
9E, American Airlines, C5, Delta, Allegiant Air, G7, Japan Airlines, Key Lime Air, Contour Aviation, MQ, OH, OO, PT, Sun Country Airlines, United, AlMasria, Southwest Airlines, Avelo Airlines, YV, YX.
Where can I go with a single stop?
561 destinations can be reached from Knoxville with a single stop. Build your itinerary on the map to find them.